In a research study involving adolescents, what document must an adolescent subject sign?

In research studies involving adolescents, the appropriate document for an adolescent subject to sign is called "assent." Assent refers to the process whereby a minor agrees to participate in a study after being adequately informed about the research in a manner that is understandable to them. This process is essential in research ethics, as it emphasizes the importance of respecting the autonomy and rights of young individuals, even though they may not have the legal capacity to provide formal informed consent, which is typically required only from adults.

While informed consent is the document provided to adults participating in studies, adolescents may be able to provide assent along with or under parental or guardian consent, depending on the regulations governing the research and the age of the adolescent. Authorization and consent for study procedures, while important in certain contexts, do not specifically pertain to the unique situation of securing agreement from adolescent subjects. Thus, the correct answer emphasizes the significance of involving the adolescent in the decision-making process regarding their participation in research.